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    Abstract: Bacterial infections caused by antibiotic-resistant isolates have become
    a major health problem in recent years, since they are very difficult to treat,
    leading to an increase in morbidity and mortality. Nitrofurantoin is a broad-
    spectrum bactericidal antibiotic that, through a complex mode of action ... Nitrofurantoin (Macrodantin, Furadantin, Macrobid) is a prescription antibiotic
    used to treat urinary tract infections. Nitrofurantoin is available in three forms,
    Macrodantin, Furadantin, and Macrobid. Common side effects are change in
    urine color, diarrhea, itching, and headache. Pregnancy and breastfeeding safety
    Nitrofurantoin is an antibiotic used to treat urinary tract infections. Learn about
    side effects, interactions and indications.
    GFR 30-45: only use if resistance & no alternative; in treatment failure: always
    perform culture. Use nitrofurantoin first line as general resistance and community
    multi-resistant. Extended-spectrum Beta-lactamase E. coli are increasing.
    Trimethoprim (if low risk of resistance) and pivmecillinam are alternative first line
    agents.
    Nitrofurantoin is commonly used to treat urinary tract infections (UTIs) in pregnant
    women. Comfort in selecting this antibiotic comes from its friendly FDA pregnancy
    category B rating and long history of safe and effective use. However, the FDA
    pregnancy category ratings can be misleading because they ...
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    Nitrofurantoin (N-(5-nitro-2-furfurylidene)-1-aminohydantoin) is an antimicrobial
    drug used in the treatment and prophylaxis of uncomplicated lower urinary tract
    infections (UTIs) (Gleckman et al., 1979; McOsker and Fitzpatrick, 1994;
    Valdevenito S, 2008). The mechanism of action of nitrofurantoin (NFT) is poorly
    understood,
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    NHS medicines information on nitrofurantoin – what it's used for, side effects,
    dosage and who can take it.
    MacrobidВ® (nitrofurantoin monohydrate/macrocrystals) Capsules. To reduce the
    development of drug-resistant bacteria and maintain the effectiveness of
    Macrobid and other antibacterial drugs, Macrobid should be used only to treat or
    prevent infections that are proven or strongly suspected to be caused by bacteria.
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